(2R,3S)-2-Hydroxy-3-(N-Tertbutoxycarbonyl) Amino-3- Phenyl- Methyl Propionate (Intermediate Of Docetaxel)
Methyl (2R,3S)-3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropionate
CAS: 124605-42-1
Molecular Formula: C15H21NO5
(2R,3S)-2-Hydroxy-3-(N-Tertbutoxycarbonyl) Amino-3- Phenyl- Methyl Propionate (Intermediate Of Docetaxel) - Names and Identifiers
(2R,3S)-2-Hydroxy-3-(N-Tertbutoxycarbonyl) Amino-3- Phenyl- Methyl Propionate (Intermediate Of Docetaxel) - Physico-chemical Properties
| Molecular Formula | C15H21NO5 |
| Molar Mass | 295.33 |
| Density | 1.170 |
| Melting Point | 132-133°C |
| Boling Point | 443.3±45.0 °C(Predicted) |
| Flash Point | 221.921°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 11.22±0.46(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.521 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Taxus. |
(2R,3S)-2-Hydroxy-3-(N-Tertbutoxycarbonyl) Amino-3- Phenyl- Methyl Propionate (Intermediate Of Docetaxel) - Introduction
(2R,3S)-N-tert-butoxycarbonyl-3-phenylisoserine methyl ester is an organic compound with the chemical formula C16H21NO5.
Nature:
The compound is a solid with the property of being soluble in ether and chloroform. It is a chiral molecule and exists as a stereoisomer. The compound is an ester compound containing a phenyl group and an isoserine methyl ester group. Its optical rotation is a specific angle, which can reflect the existence of its chirality.
Use:
(2R,3S)-N-tert-butoxycarbonyl-3-phenylisoserine methyl ester has certain applications in the field of organic synthesis. It can be used as an intermediate for the synthesis of other chiral compounds or drugs, such as synthetic enzyme inhibitors and drug precursors.
Preparation Method:
The method of synthesizing (2R,3S)-N-tert-butoxycarbonyl-3-phenylisoserine methyl ester may be by chemical synthesis. A common method is to react isoserine methyl ester with an enantioselective chiral alcohol and then couple the product with a t-butoxycarbonyl compound by appropriate esterification.
Safety Information:
The safety information about (2R,3S)-N-tert-butoxycarbonyl-3-phenylisoserine methyl ester is currently less reported. However, since it is a chemical, it must be handled and stored properly, avoiding contact with skin and eyes. During use or handling, relevant safety procedures should be followed and personal protective equipment should be worn as required. It is recommended to use the compound under the guidance of a professional.
Nature:
The compound is a solid with the property of being soluble in ether and chloroform. It is a chiral molecule and exists as a stereoisomer. The compound is an ester compound containing a phenyl group and an isoserine methyl ester group. Its optical rotation is a specific angle, which can reflect the existence of its chirality.
Use:
(2R,3S)-N-tert-butoxycarbonyl-3-phenylisoserine methyl ester has certain applications in the field of organic synthesis. It can be used as an intermediate for the synthesis of other chiral compounds or drugs, such as synthetic enzyme inhibitors and drug precursors.
Preparation Method:
The method of synthesizing (2R,3S)-N-tert-butoxycarbonyl-3-phenylisoserine methyl ester may be by chemical synthesis. A common method is to react isoserine methyl ester with an enantioselective chiral alcohol and then couple the product with a t-butoxycarbonyl compound by appropriate esterification.
Safety Information:
The safety information about (2R,3S)-N-tert-butoxycarbonyl-3-phenylisoserine methyl ester is currently less reported. However, since it is a chemical, it must be handled and stored properly, avoiding contact with skin and eyes. During use or handling, relevant safety procedures should be followed and personal protective equipment should be worn as required. It is recommended to use the compound under the guidance of a professional.
Last Update：2024-04-09 21:54:55
Supplier List
Spot supply
Product Name: Cabazitaxel Impurity 49 Visit Supplier Webpage Request for quotationCAS: 124605-42-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Methyl (2R,3S)-3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropionate Visit Supplier Webpage Request for quotationCAS: 124605-42-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Cabazitaxel Impurity 49 Visit Supplier Webpage Request for quotationCAS: 124605-42-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Methyl (2R,3S)-3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropionate Visit Supplier Webpage Request for quotationCAS: 124605-42-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History